glutathione vs guaiacol Comparative elicitation of antioxidant defense in cell suspension culture of catharanthus roseus by mycelium extract and filtrated culture medium of schizophyllum commune Download Your Exclusive Men's

Download Your Exclusive Men's Health Digital Issues

M100, 32 nd edition, 2022

single-40

Quantité:9 PCS

System Xc − transfers cystine or cystine sulfide into cells and reduces it to cysteine ( GSH is mainly composed of glutamate, cysteine, and glycine, and the sulfhydryl structure of GSH can be oxidized and dehydrogenated, making GSH an important antioxidant and free radical scavenger in the body ( − , reduce intracellular cystine uptake, decrease GSH synthesis, induce lipid peroxide accumulation, and finally lead to cell ferroptosis ( − in kidney injury ( − , thus affecting GPX4 activity, resulting in renal cell ferroptosis ( α -lipoic acid ameliorates folic acid (FA)-induced AKI by inhibiting p53 and up-regulating SLC7A11 expression ( − in tumor cells ( In summary, system Xc − can maintain GSH levels by maintaining the balance between intracellular and extracellular cystine and glutamate