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In case of a significant result ( p ≤ 0.05), the number of potentially missing studies required to make the p value nonsignificant was estimated by using the classical fail‐safe N method as another marker of publication bias

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As a result, an accumulation of Lipid-OOH occurs: since GSH is the reducing co-substrate of GPX4, able to regulate the redox state of the cell-forming Lipid-OH (Figure 2A), GSH depletion can negatively regulate GPX4, triggering ferroptosis [19]