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Lipolysis: cellular mechanisms for lipid mobilization from fat stores | Nature Metabolism

For a compound to progress from its current status to FDA approval, it would need to complete IND-enabling studies (including formal toxicology and GMP manufacturing), a Phase 1 safety trial in humans, Phase 2 efficacy and dose-finding trials, and Phase 3 confirmatory trials — a process that typically takes 8 to 15 years and costs hundreds of millions of dollars with no guarantee of success

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