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The mean abundance of Firmicutes decreased by 20.2% from baseline (mean, 16.9) to week 10 (mean, 13.5)

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It is now widely accepted that both mutations of oncogenes and tumor suppressor genes lead to the switch into an angiogenic tumor, i.e., the endogenous balance between pro-angiogenic and anti-angiogenic molecules is tipped in favor of angiogenesis (8–10)